Generation of BAC transgenic tadpoles enabling live imaging of motoneurons by using the urotensin II-related peptide (ust2b) gene as a driver.

Xenopus is an excellent tetrapod model for studying normal and pathological motoneuron ontogeny due to its developmental morpho-physiological advantages. In mammals, the urotensin II-related peptide (UTS2B) gene is primarily expressed in motoneurons of the brainstem and the spinal cord. Here, we sho...

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Bibliographic Details
Main Authors: Marion Bougerol, Frédéric Auradé, François M Lambert, Didier Le Ray, Denis Combes, Muriel Thoby-Brisson, Frédéric Relaix, Nicolas Pollet, Hervé Tostivint
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319907?pdf=render