Myogenic progenitor cell transplantation for muscle regeneration following hindlimb ischemia and reperfusion

Abstract Background Muscle is severely affected by ischemia/reperfusion injury (IRI). Quiescent satellite cells differentiating into myogenic progenitor cells (MPC) possess a remarkable regenerative potential. We herein established a model of local application of MPC in murine hindlimb ischemia/repe...

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Bibliographic Details
Main Authors: Franka Messner, Marco Thurner, Jule Müller, Michael Blumer, Julia Hofmann, Rainer Marksteiner, Sebastien Couillard-Despres, Jakob Troppmair, Dietmar Öfner, Stefan Schneeberger, Theresa Hautz
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-021-02208-w