Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.

Many studies on associations between human leukocyte antigen (HLA) allele frequencies and susceptibility to systemic lupus erythematosus (SLE) have been performed. However, few protective associations with HLA-DRB1 alleles have been reported. Here, we sought protective, as well as predispositional,...

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Main Authors: Hiroshi Furukawa, Aya Kawasaki, Shomi Oka, Ikue Ito, Kota Shimada, Shoji Sugii, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Yuya Kondo, Satoshi Ito, Taichi Hayashi, Isao Matsumoto, Makio Kusaoi, Hirofumi Amano, Tatsuo Nagai, Shunsei Hirohata, Keigo Setoguchi, Hajime Kono, Akira Okamoto, Noriyuki Chiba, Eiichi Suematsu, Masao Katayama, Kiyoshi Migita, Akiko Suda, Shigeru Ohno, Hiroshi Hashimoto, Yoshinari Takasaki, Takayuki Sumida, Shouhei Nagaoka, Naoyuki Tsuchiya, Shigeto Tohma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3912000?pdf=render