Ezh2 harnesses the intranuclear actin cytoskeleton to remodel chromatin in differentiating Th cells

Summary: Following their first interaction with the antigen, quiescent naive T-helper (Th; CD4+) cells enlarge, differentiate, and proliferate; these processes are accompanied by substantial epigenetic alterations. We showed previously that the epigenetic regulators the polycomb-group (PcG) proteins...

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Bibliographic Details
Main Authors: Moran Titelbaum, Boris Brant, Daniel Baumel, Alina Burstein-Willensky, Shira Perez, Yiftah Barsheshet, Orly Avni
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010610