Correlation between cell aggregation and antibody production in IgE-producing plasma cells

Allergic conditions result in the increase of immunoglobulin (Ig)E-producing plasma cells (IgE-PCs); however, it is unclear how IgE production is qualitatively controlled. In this study, we found that IgE-PCs in spleen of immunized mice formed homotypic cell aggregates. By employing IgE-producing hy...

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Bibliographic Details
Main Authors: Mari Hikosaka, Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
IgE
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580816303703