Effect of Epigallocatechin Gallate and Catechin on Overexpression of GSK-3β and IR Genes Induced by Streptozotocin in Rat Brain

Effect of Epigallocatechin Gallate and Catechin on Overexpression of GSK-3β and IR Genes Induced by Streptozotocin in Rat Brain

Background: Type 2 diabetes mellitus (T2DM) is one of the significant risk factors for Alzheimer disease (AD). Defects in insulin signaling pathway induce AD hallmarks mainly through activation of glycogen synthase kinase-3β (GSK-3β) pathway.  Objectives: In this study, we investigated the expressio...

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Bibliographic Details
Main Authors: Marzieh Zamani, Kambiz Rohampour, Samira Rashtiani, Masoume Dolati, Faranak Fallahian, Naser Kalhor
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2019-11-01
Series:Caspian Journal of Neurological Sciences
Subjects:
catechin
alzheimer disease
receptor insulin
glycogen synthase kinases
memory
Online Access:http://cjns.gums.ac.ir/article-1-293-en.html

Internet

http://cjns.gums.ac.ir/article-1-293-en.html

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