A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate drugs and vaccines. Using CRISPR/Cas9 methodology a transgenic Plasmodium falciparum (Pf) NF54 line was generated that expresses a fusion of mChe...

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Bibliographic Details
Main Authors: Catherin Marin-Mogollon, Ahmed M. Salman, Karin M. J. Koolen, Judith M. Bolscher, Fiona J. A. van Pul, Shinya Miyazaki, Takashi Imai, Ahmad Syibli Othman, Jai Ramesar, Geert-Jan van Gemert, Hans Kroeze, Severine Chevalley-Maurel, Blandine Franke-Fayard, Robert W. Sauerwein, Adrian V. S. Hill, Koen J. Dechering, Chris J. Janse, Shahid M. Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium falciparum
transgenes
reporters
mCherry
luciferase
CRISPR/Cas9
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00096/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00096/full

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