Novel Ferrocene Derivatives Induce G0/G1 Cell Cycle Arrest and Apoptosis through the Mitochondrial Pathway in Human Hepatocellular Carcinoma

Novel Ferrocene Derivatives Induce G0/G1 Cell Cycle Arrest and Apoptosis through the Mitochondrial Pathway in Human Hepatocellular Carcinoma

In this study, detailed information on hepatocellular carcinoma (HCC) cells (HepG-2, SMMC-7721, and HuH-7) and normal human liver cell L02 treated by ferrocene derivatives (compounds <b>1</b>, <b>2</b> and <b>3</b>) is provided. The cell viability assay showed tha...

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Bibliographic Details
Main Authors: Jianrong Zheng, Liao Zeng, Mingqing Tang, Hongjun Lin, Chao Pi, Ruian Xu, Xiuling Cui
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
human hepatocellular carcinoma
apoptosis
cell cycle
reactive oxygen species
mitochondrial membrane permeabilization
Online Access:https://www.mdpi.com/1422-0067/22/6/3097

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https://www.mdpi.com/1422-0067/22/6/3097

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