Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues

Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues

In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O-benzoylribose or activated alkylat...

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Bibliographic Details
Main Authors: Abdelaaziz Ouahrouch, Moha Taourirte, Joachim W. Engels, Soumaya Benjelloun, Hassan B. Lazrek
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
quinazoline ribonucleosides
1,2,3-triazole-acyclonucleosides
Huisgen cycloaddition
quinazolinone alkylation
HCV
Online Access:http://www.mdpi.com/1420-3049/19/3/3638

Internet

http://www.mdpi.com/1420-3049/19/3/3638

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