Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium

Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium

The electrophysiological properties underlying the automaticity of the guinea pig pulmonary vein myocardium were studied. About 30% of the isolated pulmonary vein tissue preparations showed spontaneous electrical activity, as shown by glass microelectrode recordings from their myocardial layer. The...

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Bibliographic Details
Main Authors: Yayoi Tsuneoka, Masahiko Irie, Yusuke Tanaka, Takahiko Sugimoto, Yuka Kobayashi, Taichi Kusakabe, Keisuke Kato, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Pulmonary vein myocardium
Potassium channel
Automaticity
Resting membrane potential
Intracellular Ca2+
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300427

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http://www.sciencedirect.com/science/article/pii/S1347861317300427

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