In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19

Abstract In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further cleaved into 15 non-structural proteins whereas the 3′ terminus encodes four structural proteins and eight accessory proteins. Among these 27 proteins, the present study aimed to discover likely antigenic p...

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Bibliographic Details
Main Authors: Hüseyin Can, Ahmet Efe Köseoğlu, Sedef Erkunt Alak, Mervenur Güvendi, Mert Döşkaya, Muhammet Karakavuk, Adnan Yüksel Gürüz, Cemal Ün
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79645-9