Design, Synthesis and Antimycobacterial Activity of Novel Imidazo[1,2-a]pyridine Amide-Cinnamamide Hybrids

Design, Synthesis and Antimycobacterial Activity of Novel Imidazo[1,2-a]pyridine Amide-Cinnamamide Hybrids

We report herein the design and synthesis of a series of novel imidazo[1,2-a]pyridine amide-cinnamamide hybrids linked via an alkyl carbon chain. All 38 new hybrids were evaluated for their antimycobacterial activity against M. tuberculosis (MTB) H37Rv ATCC 27294 using the microplate Alamar Blue ass...

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Bibliographic Details
Main Authors: Linhu Li, Zhuorong Li, Mingliang Liu, Weiyi Shen, Bin Wang, Huiyuan Guo, Yu Lu
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
imidazo[1,2-a]pyridine amide-cinnamamide hybrids
design
synthesis
antimycobacterial activity
Online Access:http://www.mdpi.com/1420-3049/21/1/49

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http://www.mdpi.com/1420-3049/21/1/49

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