Plasmacytoid Dendritic Cells Depletion and Elevation of IFN-γ Dependent Chemokines CXCL9 and CXCL10 in Children With Multisystem Inflammatory Syndrome

Plasmacytoid Dendritic Cells Depletion and Elevation of IFN-γ Dependent Chemokines CXCL9 and CXCL10 in Children With Multisystem Inflammatory Syndrome

BackgroundSARS-CoV-2 occurs in the majority of children as COVID-19, without symptoms or with a paucisymptomatic respiratory syndrome, but a small proportion of children develop the systemic Multi Inflammatory Syndrome (MIS-C), characterized by persistent fever and systemic hyperinflammation, with s...

Full description

Bibliographic Details
Main Authors: Francesca Caldarale, Mauro Giacomelli, Emirena Garrafa, Nicola Tamassia, Alessia Morreale, Piercarlo Poli, Silviana Timpano, Giulia Baresi, Fiammetta Zunica, Marco Cattalini, Daniele Moratto, Marco Chiarini, Elvira Stefania Cannizzo, Giulia Marchetti, Marco Antonio Cassatella, Andrea Taddio, Alberto Tommasini, Raffaele Badolato
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
multisystem inflammatory syndrome in children
CXCL9
CXCL10
plasmacytoid DCs
IFN
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654587/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654587/full

Similar Items