Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

Abstract Background Gene copy number variants (CNVs), which consist of deletions and amplifications of single or sets of contiguous genes, contribute to the great diversity in the Plasmodium falciparum genome. In vitro studies in the laboratory have revealed their important role in parasite fitness...

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Bibliographic Details
Main Authors: Joan Simam, Martin Rono, Joyce Ngoi, Mary Nyonda, Sachel Mok, Kevin Marsh, Zbynek Bozdech, Margaret Mackinnon
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Genomics
Subjects:
Copy number variation
Plasmodium falciparum
Adaptation
Online Access:http://link.springer.com/article/10.1186/s12864-018-4689-7

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http://link.springer.com/article/10.1186/s12864-018-4689-7

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