Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma

Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma

Oncolytic viruses (OVs) are emerging as powerful anti-cancer agents and are currently being tested for their safety and efficacy in patients. Reovirus (Reolysin), a naturally occurring non-pathogenic, double-stranded RNA virus, has natural oncolytic activity and is being tested in phase I–III clinic...

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Bibliographic Details
Main Authors: Alena C. Jaime-Ramirez, Jun-Ge Yu, Enrico Caserta, Ji Young Yoo, Jianying Zhang, Tae Jin Lee, Craig Hofmeister, John H. Lee, Bhavna Kumar, Quintin Pan, Pawan Kumar, Robert Baiocchi, Theodoros Teknos, Flavia Pichiorri, Balveen Kaur, Matthew Old
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
reovirus
oncolytics
head and neck cancer
immune impact
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770517300219

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http://www.sciencedirect.com/science/article/pii/S2372770517300219

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