Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells.

To explore the diversity and consistency of the signaling pathways that regulate tumor cell migration, we chose three human tumor cell lines that migrated after treatment with EGF. We then quantified the effect of fifteen inhibitors on the levels of expression or the phosphorylation levels of nine p...

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Bibliographic Details
Main Authors: Shigeyuki Magi, Yuya Saeki, Masato Kasamatsu, Etsu Tashiro, Masaya Imoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018296?pdf=render