Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes

Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes

<p>Abstract</p> <p>Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is associated with a downregulation of the pattern recogni...

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Bibliographic Details
Main Authors: Dodt Christoph, Sayk Friedhelm, van Bremen Tobias, Goldmann Torsten, Luitjens Karen, Schaaf Bernhard, Dalhoff Klaus, Droemann Daniel
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/4/1/12

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http://www.diagnosticpathology.org/content/4/1/12

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