Aplysin Sensitizes Cancer Cells to TRAIL by Suppressing P38 MAPK/Survivin Pathway

TNF-related apoptosis-inducing ligand (TRAIL) is a tumor-selective apoptosis inducer and has been shown to be promising for treating various types of cancers. However, the application of TRAIL is greatly impeded by the resistance of cancer cells to its action. Studies show that overexpression of som...

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Bibliographic Details
Main Authors: Jia Liu, Leina Ma, Ning Wu, Ge Liu, Lanhong Zheng, Xiukun Lin
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/9/5072