Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

<p>Abstract</p> <p>Background</p> <p>Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte...

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Bibliographic Details
Main Authors: Koppelmann Tal, Pollak Yulia, Mogilner Jorge, Bejar Jacob, Coran Arnold G, Sukhotnik Igor
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Gastroenterology
Subjects:
Rat
Online Access:http://www.biomedcentral.com/1471-230X/12/41