Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier

Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier

Abstract Background Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the blood-cerebrospinal fluid barrier (BCSFB), which has been demonstrated to b...

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Bibliographic Details
Main Authors: Tobias Dahm, Ortwin Adams, Sindy Boettcher, Sabine Diedrich, Vasily Morozov, Grant Hansman, Petra Fallier-Becker, Sebastian Schädler, Claus J. Burkhardt, Christel Weiss, Carolin Stump-Guthier, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Tobias Tenenbaum, Henriette Rudolph
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Enterovirus
Echovirus (E-30)
Blood-cerebrospinal fluid barrier
Outbreak strains
Tight junction
Genomic sequencing
Online Access:http://link.springer.com/article/10.1186/s12974-018-1061-4

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http://link.springer.com/article/10.1186/s12974-018-1061-4

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