Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1

CEACAM1 regulates endothelial barrier integrity. Because insulin signaling in extrahepatic target tissues is regulated by insulin transport through the endothelium, we aimed at investigating the metabolic role of endothelial CEACAM1. To this end, we generated endothelial cell-specific <i>Ceaca...

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Bibliographic Details
Main Authors: Harrison T. Muturi, Saja S. Khuder, Hilda E. Ghadieh, Emily L. Esakov, Hyelim Noh, Heejoon Kang, Marcia F. McInerney, Jason K. Kim, Abraham D. Lee, Sonia M. Najjar
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
carcinoembryonic antigen-related cell adhesion molecule-1
insulin transport
insulin clearance
insulin resistance
normo-insulinemia
Online Access:https://www.mdpi.com/2073-4409/10/8/2093

Internet

https://www.mdpi.com/2073-4409/10/8/2093

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