Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology

Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology

Myasthenia gravis (MG) is a prototypical autoantibody mediated disease. The autoantibodies in MG target structures within the neuromuscular junction (NMJ), thus affecting neuromuscular transmission. The major disease subtypes of autoimmune MG are defined by their antigenic target. The most common ta...

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Bibliographic Details
Main Authors: Miriam L. Fichtner, Ruoyi Jiang, Aoibh Bourke, Richard J. Nowak, Kevin C. O’Connor
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
myasthenia gravis
B cells
B lymphocytes
autoimmunity
immunopathology
autoantibodies
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00776/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00776/full

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