Controlled Human Infections As a Tool to Reduce Uncertainty in Clinical Vaccine Development

Vaccines can be extremely cost-effective public health measures. Unfortunately the research and development (R&D) of novel vaccines is suffering from rising costs and declining success rates. Because many vaccines target low- and middle income markets (LMIC), output needs to be maintained at...

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Bibliographic Details
Main Authors: Meta Roestenberg, Ingrid M. C. Kamerling, Saco J. de Visser
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00297/full