Age and the means of bypassing stasis are determinants of the intrinsic subtypes of immortalized human mammary epithelial cells

Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like subtype tumors comprising a majority of cases...

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Bibliographic Details
Main Authors: Jonathan K Lee, James C Garbe, Masaru eMiyano, Martha R Stampfer, Mark A LaBarge
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00013/full