Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter

Role of Endothelial and Mesenchymal Cell Transitions in Heart Failure and Recovery Thereafter

Background: Mechanisms of myocardial recovery are not well elucidated.Methods: 3-month-old C57/BL6 mice were treated with Angiotensin-II infusion and N (w)-nitro-L-arginine methyl ester in drinking water to induce HF at 5 weeks. These agents were discontinued, and animals studied with echocardiograp...

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Bibliographic Details
Main Authors: Guangyu Wang, Ana Sofia Cruz, Keith Youker, Hernan G. Marcos-Abdala, Rajarajan A. Thandavarayan, John P. Cooke, Guillermo Torre-Amione, Kaifu Chen, Arvind Bhimaraj
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
heart failure
cardiac recovery
endothelial to mesenchymal transition
mesenchymal to endothelial transition
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.609262/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.609262/full

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