Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations

Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations

<p>Abstract</p> <p>Background</p> <p>The sickle (β<sup>s</sup>) mutation in the <it>beta-globin </it>gene (HBB) occurs on five "classical" β<sup>s </sup>haplotype backgrounds in ethnic groups of African ancestry. Strong sele...

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Bibliographic Details
Main Authors: Jallow Muminatou, Pinder Margaret, Rockett Kirk, Trafford Clare, Elzein Abier, Hanchard Neil, Harding Rosalind, Kwiatkowski Dominic, McKenzie Colin
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/8/52

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http://www.biomedcentral.com/1471-2156/8/52

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