Klotho inhibits neuronal senescence in human brain organoids
Abstract Aging is a major risk factor for many neurodegenerative diseases. Klotho (KL) is a glycosylated transmembrane protein that is expressed in the choroid plexus and neurons of the brain. KL exerts potent anti-aging effects on multiple cell types in the body but its role in human brain cells re...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-08-01
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| Series: | npj Aging and Mechanisms of Disease |
| Online Access: | https://doi.org/10.1038/s41514-021-00070-x |