Mucolytic Effectiveness of Tyloxapol in Chronic Obstructive Pulmonary Disease - A Double-Blind, Randomized Controlled Trial.

OBJECTIVE:Mucoactive drugs should increase the ability to expectorate sputum and, ideally, have anti-inflammatory properties. The aim of the study was to evaluate the mucolytic activity of Tyloxapol compared to saline (0.9%) in COPD. DESIGN:A randomized, placebo-controlled, double-blinded crossover,...

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Bibliographic Details
Main Authors: Martin Koppitz, Charlotte Eschenburg, Emilia Salzmann, Martin Rosewich, Ralf Schubert, Stefan Zielen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4911120?pdf=render