Effects of Normoxia, Hyperoxia, and Mild Hypoxia on Macro-Hemodynamics and the Skeletal Muscle Microcirculation in Anesthetised Rats

Effects of Normoxia, Hyperoxia, and Mild Hypoxia on Macro-Hemodynamics and the Skeletal Muscle Microcirculation in Anesthetised Rats

Objectives: Excessive oxygen (O2) administration may have a negative impact on tissue perfusion by inducing vasoconstriction and oxidative stress. We aimed to evaluate the effects of different inhaled oxygen fractions (FiO2) on macro-hemodynamics and microvascular perfusion in a rat model.Methods: I...

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Bibliographic Details
Main Authors: Elisa Damiani, Erika Casarotta, Fiorenza Orlando, Andrea Carsetti, Claudia Scorcella, Roberta Domizi, Erica Adrario, Silvia Ciucani, Mauro Provinciali, Abele Donati
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Medicine
Subjects:
hyperoxia
hypoxia
microcirculation
oxygen
hemodymamics
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.672257/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.672257/full

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