Dencichine prevents ovariectomy-induced bone loss and inhibits osteoclastogenesis by inhibiting RANKL-associated NF-κB and MAPK signaling pathways

Aims: To investigate the effect of dencichine on osteoclastogenesis in vivo and in vitro. Methods: RANKL-induced osteoclastogenesis were treated with different concentrations of dencichine. Pit forming assays were applied to evaluate the degree of bone resorption. Osteoclastogenic markers were detec...

Full description

Bibliographic Details
Main Authors: Dingwei Cang, Guoyou Zou, Chi Yang, Xiaofei Shen, Feng Li, Ya Wu, Biao Ji
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000372