Permeation characteristics of tetracyclines in parallel artificial membrane permeation assay

The purpose of the present study was to characterize the passive permeation of tetracyclines in the parallel artificial membrane permeation assay (PAMPA). Tetracyclines exist as zwitterion at physiological pH. The PAMPA membrane was prepared by impregnating a phospholipid/decane solution to a filter...

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Bibliographic Details
Main Authors: Sachika Yamauchi, Kiyohiko Sugano
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2019-08-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/657