Establishment of the Inducible Tet-On System for the Activation of the Silent Trichosetin Gene Cluster in Fusarium fujikuroi

Establishment of the Inducible Tet-On System for the Activation of the Silent Trichosetin Gene Cluster in Fusarium fujikuroi

The PKS-NRPS-derived tetramic acid equisetin and its N-desmethyl derivative trichosetin exhibit remarkable biological activities against a variety of organisms, including plants and bacteria, e.g., Staphylococcus aureus. The equisetin biosynthetic gene cluster was first described in Fusarium heteros...

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Bibliographic Details
Main Authors: Slavica Janevska, Birgit Arndt, Leonie Baumann, Lisa Helene Apken, Lucas Maciel Mauriz Marques, Hans-Ulrich Humpf, Bettina Tudzynski
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Toxins
Subjects:
Fungi
Fusarium fujikuroi
secondary metabolism
PKS-NRPS
biosynthesis
gene regulation
Online Access:http://www.mdpi.com/2072-6651/9/4/126

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http://www.mdpi.com/2072-6651/9/4/126

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