The Reduced Folate Carrier (RFC-1) 80A>G Polymorphism and Maternal Risk of Having a Child with Down Syndrome: A Meta-Analysis

A common polymorphism (c.80A>G) in the gene coding for the reduced folate carrier (SLC19A1, commonly known as RFC-1) has been associated with maternal risk of the birth of a child with Down Syndrome (DS), but results are controversial. We searched major online databases to identify available case...

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Bibliographic Details
Main Authors: Lucia Migliore, Valentina Lorenzoni, Fabio Coppedè
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/5/7/2551