A novel mechanism of antibody-mediated enhancement of flavivirus infection.

Antibody-dependent enhancement of viral infection is a well-described phenomenon that is based on the cellular uptake of infectious virus-antibody complexes following their interaction with Fcγ receptors expressed on myeloid cells. Here we describe a novel mechanism of antibody-mediated enhancement...

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Bibliographic Details
Main Authors: Denise Haslwanter, Dieter Blaas, Franz X Heinz, Karin Stiasny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5617232?pdf=render