Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin

Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin

<p>Abstract</p> <p>Background</p> <p>Skin is the largest organ in the body, and is directly exposed to extrinsic assaults. As such, the skin plays a central role in host defense and the cutaneous immune system is able to elicit specific local inflammatory and systemic i...

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Bibliographic Details
Main Authors: Wei Wen-Chi, Lin Sheng-Yen, Chen Yi-Jyun, Wen Chih-Chun, Huang Chiung-Yao, Palanisamy Arulselvan, Yang Ning-Sun, Sheu Jyh-Horng
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Biomedical Science
Subjects:
Briarane-type diterpene
TPA-induced mouse dermatitis
Dendritic cells
Vascular permeability
Edema
Online Access:http://www.jbiomedsci.com/content/18/1/94

Internet

http://www.jbiomedsci.com/content/18/1/94

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