Losartan prevents heart fibrosis induced by long-term intensive exercise in an animal model.

<h4>Rationale</h4>Recently it has been shown that long-term intensive exercise practice is able to induce myocardial fibrosis in an animal model. Angiotensin II is a profibrotic hormone that could be involved in the cardiac remodeling resulting from endurance exercise.<h4>Objective...

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Bibliographic Details
Main Authors: Gemma Gay-Jordi, Eduard Guash, Begoña Benito, Josep Brugada, Stanley Nattel, Lluís Mont, Anna Serrano-Mollar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23383330/?tool=EBI