Tuning the Tumor Myeloid Microenvironment to Fight Cancer

Tuning the Tumor Myeloid Microenvironment to Fight Cancer

The tumor microenvironment (TME) of diverse cancer types is often characterized by high levels of infiltrating myeloid cells including monocytes, macrophages, dendritic cells, and granulocytes. These cells perform a variety of functions in the TME, varying from immune suppressive to immune stimulato...

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Bibliographic Details
Main Authors: Nadine S. Jahchan, Adriana M. Mujal, Joshua L. Pollack, Mikhail Binnewies, Venkataraman Sriram, Leonard Reyno, Matthew F. Krummel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
tumor micoenvironment
macrophage
tumor associated macrophage (TAM)
immune checkpoint blockade (ICB)
dendritic cell (DC)
myeloid cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01611/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01611/full

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