An Insulin-Like Modular Basis for the Evolution of Glucose Transporters (GLUT) with Implications for Diabetes

Glucose transporters (GLUT) are twelve-transmembrane spanning proteins that contain two pores capable of transporting glucose and dehydroascorbate in and out of cells. The mechanism by which transport is effected is unknown. An evolutionarily-based hypothesis for the mechanism of glucose transport i...

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Bibliographic Details
Main Author: Robert Root-Bernstein
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Evolutionary Bioinformatics
Online Access:http://la-press.com/article.php?article_id=408