Bone marrow alterations and lower endothelial progenitor cell numbers in critical limb ischemia patients.

Bone marrow alterations and lower endothelial progenitor cell numbers in critical limb ischemia patients.

Critical limb ischemia (CLI) is characterized by lower extremity artery obstruction and a largely unexplained impaired ischemic neovascularization response. Bone marrow (BM) derived endothelial progenitor cells (EPC) contribute to neovascularization. We hypothesize that reduced levels and function o...

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Bibliographic Details
Main Authors: Martin Teraa, Ralf W Sprengers, Peter E Westerweel, Hendrik Gremmels, Marie-José T H Goumans, Tom Teerlink, Frans L Moll, Marianne C Verhaar, JUVENTAS study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561321?pdf=render

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http://europepmc.org/articles/PMC3561321?pdf=render

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