Broad Neutralization as a Byproduct of Antibody Maturation during HIV-1 Infection: a Personal Perspective
Broadly neutralizing antibodies (bnAbs) may be key for an effective HIV-1 vaccine. Although bnAbs can be detected in a small percentage of HIV-1-infected individuals, they have not been successfully elicited by any vaccines. Germline ancestors of bnAbs generally do not neutralize HIV-1, but they can...
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Format: | Article |
Language: | English |
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International Biological and Medical Journals Publishing House Co., Limited
2016-07-01
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Series: | Infectious Diseases and Translational Medicine |
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Online Access: | http://www.tran-med.com/EN/abstract/abstract25.shtml |