Broad Neutralization as a Byproduct of Antibody Maturation during HIV-1 Infection: a Personal Perspective

Broad Neutralization as a Byproduct of Antibody Maturation during HIV-1 Infection: a Personal Perspective

Broadly neutralizing antibodies (bnAbs) may be key for an effective HIV-1 vaccine. Although bnAbs can be detected in a small percentage of HIV-1-infected individuals, they have not been successfully elicited by any vaccines. Germline ancestors of bnAbs generally do not neutralize HIV-1, but they can...

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Bibliographic Details
Main Author: Feng Gao
Format: Article
Language:English
Published: International Biological and Medical Journals Publishing House Co., Limited 2016-07-01
Series:Infectious Diseases and Translational Medicine
Subjects:
HIV-1
Broadly neutralizing antibody
Byproduct
Antibody maturation
Neutralization breadth
Escape
Online Access:http://www.tran-med.com/EN/abstract/abstract25.shtml

Internet

http://www.tran-med.com/EN/abstract/abstract25.shtml

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