Inhibition of Neuroinflammation by AIBP: Spinal Effects upon Facilitated Pain States

Inhibition of Neuroinflammation by AIBP: Spinal Effects upon Facilitated Pain States

Apolipoprotein A-I binding protein (AIBP) reduces lipid raft abundance by augmenting the removal of excess cholesterol from the plasma membrane. Here, we report that AIBP prevents and reverses processes associated with neuroinflammatory-mediated spinal nociceptive processing. The mechanism involves...

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Bibliographic Details
Main Authors: Sarah A. Woller, Soo-Ho Choi, Eun Jung An, Hann Low, Dina A. Schneider, Roshni Ramachandran, Jungsu Kim, Yun Soo Bae, Dmitri Sviridov, Maripat Corr, Tony L. Yaksh, Yury I. Miller
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Cell Reports
Subjects:
cholesterol
lipid rafts
inflammation
neuroinflammation
AIBP
TLR4
neuropathic pain
allodynia
chemotherapy
chronic pain
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718307101

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http://www.sciencedirect.com/science/article/pii/S2211124718307101

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