Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors

Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors

<p>Abstract</p> <p>Background</p> <p>During skeletogenesis, protein levels of β-catenin in the canonical Wnt signaling pathway determine lineage commitment of skeletal precursor cells to osteoblasts and chondrocytes. Adenomatous polyposis coli (Apc) is a key controller...

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Bibliographic Details
Main Authors: Löwik Clemens WGM, Akçakaya Pinar, Rawadi Georges, Kronenberg Henry M, Kobayashi Tatsuya, van der Valk Martin A, van der Horst Geertje, Bosch Cathy AJ, Karperien Marcel, Miclea Razvan L, Fodde Riccardo, Wit Jan, Robanus-Maandag Els C
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/9/26

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http://www.biomedcentral.com/1471-213X/9/26

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