Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

<p>Abstract</p> <p>Background</p> <p>The 90-kDa ribosomal S6 kinase (Rsk) family is involved in cell survival. Rsk activation is regulated by sequential phosphorylations controlled by extracellular signal-regulated kinase (ERK) 1/2 and 3-phosphoinositide-dependent prote...

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Bibliographic Details
Main Authors: Rué Laura, Anglada-Huguet Marta, Xifró Xavier, Saavedra Ana, Pérez-Navarro Esther, Alberch Jordi
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Molecular Neurodegeneration
Subjects:
ERK
Online Access:http://www.molecularneurodegeneration.com/content/6/1/74