Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity
<p>Abstract</p> <p>Background</p> <p>The 90-kDa ribosomal S6 kinase (Rsk) family is involved in cell survival. Rsk activation is regulated by sequential phosphorylations controlled by extracellular signal-regulated kinase (ERK) 1/2 and 3-phosphoinositide-dependent prote...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-10-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://www.molecularneurodegeneration.com/content/6/1/74 |