Pharmacodynamic effects of the K+ binder patiromer in a novel chronic hyperkalemia model in spontaneously hypertensive rats

Abstract Currently described hyperkalemia (HK) animal models are typically acute and cause significant distress and mortality to the animals, warranting new approaches for studying chronic HK in a more appropriate clinical setting. Using the spontaneously hypertensive rat (SHR) model as a more relev...

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Bibliographic Details
Main Authors: Sai Prasad N. Iyer, Lawrence Lee, Lingyun Li
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14572