Immune-modulating Activity of Hydrogel Microparticles Contributes to the Host Defense in a Murine Model of Cutaneous Anthrax

Immune-modulating Activity of Hydrogel Microparticles Contributes to the Host Defense in a Murine Model of Cutaneous Anthrax

We recently reported that the open-mesh (0.7 μ) polyacrylamide microparticles (MPs) with internally-coupled Cibacron affinity dye demonstrate protective effect in mice challenged into footpads with high doses (200 LD50) of anthrax (Sterne) spores. A single injection of MPs before spore challenge red...

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Bibliographic Details
Main Authors: Allison L. Teunis, Taissia G. Popova, Virginia Espina, Lance A. Liotta, Serguei G. Popov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
anthrax
microparticles
hydrogel
chemokines
mice
survival
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00062/full

Internet

http://journal.frontiersin.org/article/10.3389/fmolb.2017.00062/full

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