Immune antibodies and helminth products drive CXCR2-dependent macrophage-myofibroblast crosstalk to promote intestinal repair.

Helminth parasites can cause considerable damage when migrating through host tissues, thus making rapid tissue repair imperative to prevent bleeding and bacterial dissemination particularly during enteric infection. However, how protective type 2 responses targeted against these tissue-disruptive mu...

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Bibliographic Details
Main Authors: Julia Esser-von Bieren, Beatrice Volpe, Duncan B Sutherland, Jérôme Bürgi, J Sjef Verbeek, Benjamin J Marsland, Joseph F Urban, Nicola L Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004778