Dynamic Changes in Circulating Tumor DNA During Chemoradiation for Locally Advanced Lung Cancer

Purpose: Concurrent chemoradiation therapy (CRT) is the principal treatment modality for locally advanced lung cancer. Cell death due to CRT leads to the release of cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) into the bloodstream, but the kinetics and characteristics of this process are...

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Bibliographic Details
Main Authors: Michael N. Corradetti, MD, PhD, Jordan A. Torok, MD, Ace J. Hatch, PhD, Eric P. Xanthopoulos, MD, JD, Kyle Lafata, PhD, Corbin Jacobs, MD, Christel Rushing, MA, John Calaway, PhD, Greg Jones, MS, Chris R. Kelsey, MD, Andrew B. Nixon, PhD
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109419300582