Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents

Repurposing the anticancer drug cisplatin with the aim of developing novel Pseudomonas aeruginosa infection control agents

Antibiotic resistance threatens effective treatment of microbial infections globally. This situation has spurred the hunt for new antimicrobial compounds in both academia and the pharmaceutical industry. Here, we report how the widely used antitumor drug cisplatin may be repurposed as an effective a...

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Bibliographic Details
Main Authors: Mingjun Yuan, Song Lin Chua, Yang Liu, Daniela I. Drautz-Moses, Joey Kuok Hoong Yam, Thet Tun Aung, Roger W. Beuerman, May Margarette Santillan Salido, Stephan C. Schuster, Choon-Hong Tan, Michael Givskov, Liang Yang, Thomas E. Nielsen
Format: Article
Language:English
Published: Beilstein-Institut 2018-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
biofilm
cisplatin
Pseudomonas aeruginosa
resistance
type III secretion
Online Access:https://doi.org/10.3762/bjoc.14.284

Internet

https://doi.org/10.3762/bjoc.14.284

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