Brain immune interactions and air pollution: Macrophage inhibitory factor (MIF), Prion cellular protein (PrPC), Interleukin-6 (IL-6), Interleukin 1 receptor antagonist (IL-1Ra), and Interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe versus low air pollution.

Brain immune interactions and air pollution: Macrophage inhibitory factor (MIF), Prion cellular protein (PrPC), Interleukin-6 (IL-6), Interleukin 1 receptor antagonist (IL-1Ra), and Interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe versus low air pollution.

Mexico City Metropolitan Area children chronically exposed to high concentrations of air pollutants exhibit an early brain imbalance in genes involved in oxidative stress, inflammation, innate and adaptive immune responses along with accumulation of misfolded proteins observed in the early stages of...

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Bibliographic Details
Main Authors: Lilian eCalderon-Garciduenas, Janet V Cross, Maricela eFranco-Lira, Mariana eAragon-Flores, Michael eKavanaugh, Ricardo eTorres-Jardon, Chih-kai eChao, Charles eThompson, Jing eChang, Hongtu eZhu, Amedeo eD'Angiulli
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neuroscience
Subjects:
Air Pollution
Particulate Matter
Alzheimer
innate immunity
Children
neurodegeneration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00183/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00183/full

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