Effect of Crystallinity on the Properties of Polycaprolactone Nanoparticles Containing the Dual FLAP/mPEGS-1 Inhibitor BRP-187

Effect of Crystallinity on the Properties of Polycaprolactone Nanoparticles Containing the Dual FLAP/mPEGS-1 Inhibitor BRP-187

Seven polycaprolactones (PCL) with constant hydrophobicity but a varying degree of crystallinity prepared from the constitutional isomers ε-caprolactone (εCL) and δ-caprolactone (δCL) were utilized to formulate nanoparticles (NPs). The aim was to investigate the effect of the crystallinity of the bu...

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Bibliographic Details
Main Authors: Antje Vollrath, Christian Kretzer, Baerbel Beringer-Siemers, Blerina Shkodra, Justyna A. Czaplewska, Damiano Bandelli, Steffi Stumpf, Stephanie Hoeppener, Christine Weber, Oliver Werz, Ulrich S. Schubert
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Polymers
Subjects:
polycaprolactone (PCL)
polyesters
hydrophobic-hydrophilic balance (HHB)
nanoparticle formulation
nanoparticle crystallinity
FLAP antagonist
Online Access:https://www.mdpi.com/2073-4360/13/15/2557

Internet

https://www.mdpi.com/2073-4360/13/15/2557

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